Diethyl 2-Acetamidomalonate

CAS: 1068-90-2

Ref. TR-D443130

Product Information

• Name: Diethyl 2-Acetamidomalonate
• Synonyms: Propanedioic acid, 2-(acetylamino)-, 1,3-diethyl ester, Malonic acid, acetamido-, diethyl ester (6CI,7CI,8CI), Propanedioic acid, (acetylamino)-, diethyl ester (9CI), (Acetylamino)malonic acid diethyl ester, (Acetylamino)propanedioic acid diethyl ester, 2-(Acetylamino)propanedioic acid diethyl ester, 2-Acetylamino-malonic acid diethyl ester, Acetamidomalonic acid diethyl ester, Diethyl (N-acetylamino)malonate, Diethyl (acetylamino)malonate, Diethyl 2-(acetamido)propanedioate, Diethyl 2-(acetylamino)propanedioate, Diethyl 2-acetylaminomalonate, Diethyl acetamidomalonate, Diethyl a-(acetylamino)malonate, NSC 7645, (Acetylamino)-Propanedioicacidiethylester, 1,3-Diethyl 2-acetamidopropanedioate, Acetamido-Malonicacidiethylester, Acetamidomalonate de diethyle, Acetamidomalonato De Dietilo, Acetamidomalonic acid diethyl ester(Diethyl acetamidomalonate), Acetaminomalonic Acid Diethyl Ester, Acetaminomalonicaciddiethylester, Diethy acetamino Malonate, Diethyl (Acetylamino)Propanedioate, Diethyl (N-acetylamino)propanedioate, Diethyl 2-(acetylamino)malonate, Diethyl Acetaminomalonate, Diethyl acetamido malonate, Diethyl acetamidomatonate, Diethyl acetoamidomalonate, Diethyl acetylaminomalonate, Diethyl α-(acetylamino)malonate, Diethyl-2-acetamidomalonate, Diethylacetamidomalonat, Diethylacetamidomalonate, Malonic acid, acetamido-, diethyl ester, Nsc 7645, Propanedioic Acid, (Acetylamino)-, Diethyl Ester, Propanedioic acid, 2-(acetylamino)-, 1,3-diethyl ester, Ropanedioic Acid, (Acetylamino)-, Diethyl Ester, a-Diethyl acetamidomalonate

Description

Applications Diethyl 2-Acetamidomalonate, is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the preparation of Novobiocin (N888500) analogues as potential heat shock protein 90 inhibitors.
References Gunaherath, G. M., et al.: Bioorg. Med. Chem., 21, 5118 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 217.22
• Formula: C₉H₁₅NO₅
• Color/Form: Neat
• InChI: InChI=1S/C9H15NO5/c1-4-14-8(12)7(10-6(3)11)9(13)15-5-2/h7H,4-5H2,1-3H3,(H,10,11)
• InChI key: InChIKey=ISOLMABRZPQKOV-UHFFFAOYSA-N
• SMILES: CCOC(=O)C(NC(C)=O)C(=O)OCC