Diethyl 2-Acetamidomalonate

CAS: 1068-90-2

Ref. TR-D443130

Product Information

• Name: Diethyl 2-Acetamidomalonate
• Synonyms: Propanedioic acid, 2-(acetylamino)-, 1,3-diethyl ester, Malonic acid, acetamido-, diethyl ester (6CI,7CI,8CI), Propanedioic acid, (acetylamino)-, diethyl ester (9CI), (Acetylamino)malonic acid diethyl ester, (Acetylamino)propanedioic acid diethyl ester, 2-(Acetylamino)propanedioic acid diethyl ester, 2-Acetylamino-malonic acid diethyl ester, Acetamidomalonic acid diethyl ester, Diethyl (N-acetylamino)malonate, Diethyl (acetylamino)malonate, Diethyl 2-(acetamido)propanedioate, Diethyl 2-(acetylamino)propanedioate, Diethyl 2-acetylaminomalonate, Diethyl acetamidomalonate, Diethyl α-(acetylamino)malonate, NSC 7645
• Brand: TRC
• Description: Applications Diethyl 2-Acetamidomalonate, is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the preparation of Novobiocin (N888500) analogues as potential heat shock protein 90 inhibitors.References Gunaherath, G. M., et al.: Bioorg. Med. Chem., 21, 5118 (2013)

Chemical properties

• Molecular weight: 217.22
• Formula: C₉H₁₅NO₅
• Color/Form: White
• InChI: InChI=1S/C9H15NO5/c1-4-14-8(12)7(10-6(3)11)9(13)15-5-2/h7H,4-5H2,1-3H3,(H,10,11)
• InChI key: InChIKey=ISOLMABRZPQKOV-UHFFFAOYSA-N
• SMILES: CCOC(=O)C(NC(C)=O)C(=O)OCC