Diethyl 2,2'-(1,3-Dithietane-2,4-diylidene)bis(cyanoacetate)

CAS: 22624-54-0

Ref. TR-D444215

Product Information

• Name: Diethyl 2,2'-(1,3-Dithietane-2,4-diylidene)bis(cyanoacetate)
• Synonyms: 2,2'-(1,3-Dithietane-2,4-diylidene)bis[2-cyano-acetic Acid, 1,3-Dithietane, acetic acid deriv, α,α'-Dicyano-1,3-dithietane-Δ2,α:4,α'-diacetic Acid
• Brand: TRC

Description

Applications Diethyl 2,2'-(1,3-Dithietane-2,4-diylidene)bis(cyanoacetate) is used in the synthesis of Olanzapine Thiohydroxymethylidene Impurity (O253795), which is a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity.
References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)

Chemical properties

• Molecular weight: 310.35
• Formula: C₁₂H₁₀N₂O₄S₂
• Color/Form: Neat
• InChI: InChI=1S/C12H10N2O4S2/c1-3-17-9(15)7(5-13)11-19-12(20-11)8(6-14)10(16)18-4-2/h3-4H2,1-2H3
• SMILES: CCOC(=O)C(C#N)=c1sc(=C(C#N)C(=O)OCC)s1