DIFO-Biotin

Ref. TR-D445355

Product Information

• Name: DIFO-Biotin
• Synonyms: N-(1-((6,6-Difluorocyclooct-4-yn-1-yl)oxy)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
• Brand: TRC

Description

Applications DIFO-Biotin is a is a modified biotin compound with a bioorthogonal functional group. The cyclooctyne ring within the probe provides a an imaging technique that displays no cellular toxicity. Useful in the detection and isolation of metabolytes.
References Kim, E. et al.: Carb. Res., 377, 18 (2013); Baskin, J. et al.: Proc. Natl. Acad. Sci. U.S.A., 104, 16792 (2007);

Chemical properties

• Molecular weight: 646.787
• Formula: C₃₀H₄₈F₂N₄O₇S
• Color/Form: Neat
• InChI: InChI=1S/C30H48F2N4O7S/c31-30(32)11-4-3-7-23(10-12-30)43-21-27(38)34-14-6-16-41-18-20-42-19-17-40-15-5-13-33-26(37)9-2-1-8-25-28-24(22-44-25)35-29(39)36-28/h23-25,28H,1-3,5-10,12-22H2,(H,33,37)(H,34,38)(H2,35,36,39)/t23?,24-,25-,28-/m0/s1
• SMILES: O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)NCCCOCCOCCOCCCNC(=O)COC1CCC#CC(F)(F)CC1