Difenoxin

CAS: 28782-42-5

Ref. TR-D445413

Product Information

• Name: Difenoxin
• Synonyms: 1-(3-Cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic Acid, Diphenoxylic Acid, 1-(3-Cyan-3,3-diphenylpropyl)-4-phenyl-4-piperidincarbonsaeure, 1-(3-Cyano-3,3-Diphenylpropyl)-4-Phenylpiperidine-4-Carboxylic Acid, 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylic acid, 1-(3-Cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid, 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, DEA No. 9168, Difenossina, Difenossina [DCIT], Difenoxilic acid, Difenoxin [USAN:INN:BAN], Difenoxina, Difenoxina [INN-Spanish], Difenoxine, Difenoxinum, Difenoxinum [INN-Latin], Difenoxylic acid, Diphenoxin, Diphenoxylic acid, Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, Lyspafen, McN-JR 15,403-11, Unii-3Zz5Bj9F2Q

Description

Applications Difenoxin is the active metabolite of Diphenoxylate. Antiperistaltic; antidiarrheal. This is a controlled substance (opiate).
References Soudijin, W., et al.: Arzneim.-Forsch., 22, 513 (1972; Megens, A.A., et al.: Eur. J. Pharma.,178, 357 (1990)

• Brand: TRC

Chemical properties

• Molecular weight: 424.534
• Formula: C₂₈H₂₈N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C28H28N2O2/c29-22-28(24-12-6-2-7-13-24,25-14-8-3-9-15-25)18-21-30-19-16-27(17-20-30,26(31)32)23-10-4-1-5-11-23/h1-15H,16-21H2,(H,31,32)
• InChI key: InChIKey=DZHLAHOIYQLAQU-UHFFFAOYSA-N
• SMILES: N#Cc1ccccc1-c1cc(-c2ccccn2)cn(-c2ccccc2)c1=O