Diflorasone

CAS: 2557-49-5

Ref. TR-D445495

Product Information

• Name: Diflorasone
• Synonyms: (6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,17,21-trihydroxy-16beta-methyl- (8CI), (6Alpha,11Beta,16Beta)-6,9-Difluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, (6α,11β,16β)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione, Diflorason, Diflorasona, Diflorasona [INN-Spanish], Diflorasone [INN:BAN], Diflorasonum, Diflorasonum [INN-Latin], Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16β)-, Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-16β-methyl-, Unii-T2Dhj9645W

Description

Applications An anti-inflammatory and anti-itching corticosteroid usually present in topical creams.
References Pedemonte, N., et al.: Am. J. Physiol., 298, C866 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 410.45
• Formula: C₂₂H₂₈F₂O₅
• Color/Form: Neat
• InChI: InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1
• InChI key: InChIKey=WXURHACBFYSXBI-XHIJKXOTSA-N
• SMILES: C[C@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO