Diflunisal

CAS: 22494-42-4

Ref. TR-D445751

Product Information

• Name: Diflunisal
• Synonyms: 3-Biphenylcarboxylic acid, 2',4'-difluoro-4-hydroxy-, 2',4'-Difluoro-4-hydroxy-1,1'-biphenyl-3-carboxylic acid, 2',4'-Difluoro-4-hydroxybiphenyl-3-carboxylic acid, 5-(2,4-Difluorophenyl)salicylic acid, Adomal, Difludol, Diflusinal, Dolisal, Doloban, Dolobid, Dolobis, Flovacil, Fluniget, Fluodonil, Flustar, MK 647, 2',4'-Difluoro-4-Hydroxybiphenyl-3-Carboxylic Acid, 2-Hydroxy-5-(2,4-difluorophenyl)benzoic acid, 2′,4′-Difluoro-4-hydroxy[1,1′-biphenyl]-3-carboxylic acid, 2′,4′-Difluoro-4-hydroxybiphenyl-3-carboxylic acid, 3-Biphenylcarboxylic acid, 2',4'-difluoro-4-hydroxy-, 3-Biphenylcarboxylic acid, 2′,4′-difluoro-4-hydroxy-, 5-(2,4-Difluorophenyl) salicylic acid, 5-(3,4-Difluorophenyl)-2-Hydroxy-Benzoic Acid, Mk 647, [1,1'-Biphenyl]-3-carboxylic acid, 2',4'-difluoro-4-hydroxy-, [1,1′-Biphenyl]-3-carboxylic acid, 2′,4′-difluoro-4-hydroxy-

Description

Applications Diflunisal acts as an analgesic agent, used in Alzheimer’s studies (1,2,3) as an anti-inflammatory. As well as in autolytic regulation of human kallikrein -related peptidase 6 (4).
References 1. Little, S. et al.: J Biol Chem. 1997 Oct 3;272(40):25135-42.2. Diamandis, E. et al.: Clin. Biochem. 2000 Jul;33(5):369-75.3. Hutchinson, S. et al.: Clin. Chem. 2003 May;49(5):746-51. 4. Baber, S et al.: Biochemistry. 2007 May 1;46(17):5209-17.

• Brand: TRC

Chemical properties

• Molecular weight: 250.20
• Formula: C₁₃H₈F₂O₃
• Color/Form: Neat
• InChI: InChI=1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)
• InChI key: InChIKey=HUPFGZXOMWLGNK-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(-c2ccc(F)cc2F)ccc1O