1-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole

CAS: 86386-76-7

Ref. TR-D446045

Product Information

• Name: 1-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole
• Synonyms: 1H-1,2,4-Triazole, 1-[[2-(2,4-difluorophenyl)-2-oxiranyl]methyl]-, 1H-1,2,4-Triazole, 1-[[2-(2,4-difluorophenyl)oxiranyl]methyl]- (9CI), 1-[[2-(2,4-Difluorophenyl)-2-oxiranyl]methyl]-1H-1,2,4-triazole, 1-[[2-(2,4-Difluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole, 2-(2,4-Difluorophenyl)-2,3-epoxy-1-(1H-1,2,4-triazol-1-yl)propane, 2-(2,4-Difluorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane, 1-[[(2RS)-2-(2,4-Difluorophenyl)oxiran-2-yl]methyl]-1H-1,2,4-triazole
• Brand: TRC

Description

Impurity Fluconazole EP Impurity G
Applications 1-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole (Fluconazole EP Impurity G) is an epoxy impurity of the antifungal agent Fluconazole (F421000).
References Bourichi, H. et al.: STP Pharm. Prat., 18, 285 (2008); Dongre, V.G. et al.: J. Pharmac. Biomed. Anal., 42, 334 (2006):

Chemical properties

• Molecular weight: 237.21
• Formula: C₁₁H₉F₂N₃O
• Color/Form: Neat
• InChI: InChI=1S/C11H9F2N3O/c12-8-1-2-9(10(13)3-8)11(5-17-11)4-16-7-14-6-15-16/h1-3,6-7H,4-5H2
• InChI key: InChIKey=UIXQTZYZQHYHRL-UHFFFAOYSA-N
• SMILES: Fc1ccc(C2(Cn3cncn3)CO2)c(F)c1