Diglycolic Acid

CAS: 110-99-6

Ref. TR-D446330

Product Information

• Name: Diglycolic Acid
• Synonyms: 2,2'-Oxybis-Acetic Acid, Oxydi-acetic Acid, 2,2'-Oxydiacetic Acid, 3-Oxapentane-1,5-dioic Acid, 3-Oxapentanedioic Acid, Bis(carboxymethyl) Ether, NSC 8651, Oxodiacetic Acid, Oxybisacetic Acid, Oxydiacetic Acid, Oxydiethanolic Acid, 2,2'-Oxydiacetate, 2,2-Oxydiacetic acid, 2,2′-Oxybis[acetic acid], 2-(Carboxymethoxy)acetic acid, 3-Oxapentane-1,5-dioic acid, 3-Oxapentanedioic acid, Acetic acid, 2,2′-oxybis-, Acetic acid, oxydi-, Bis(carboxymethyl) ether, Diglycollic Acid, Diglylollic Acid, Oxodiacetic acid, Oxybisacetic acid, Oxydiacetic acid, Oxydiethanolic acid

Description

Applications Diglycolic Acid is a known metabolite of Diethylene Glycol(D444285) and acts as a nephrotoxic agent in human proximal renal tubule cells. It is also used in the synthesis of N-interlinked imipramines which show apoptotic activity against malignant cells as well as signs of combatting Burkitt’s lymphoma.
References Landry, G. et al.: Toxicol. Sci., 124, 35 (2011); Besenhofer, L. et al.: Toxicol. Sci., 123, 374 (2011); Bright, S. et al.: Bioorg. Med. Chem. Lett., 23, 1220 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 134.09
• Formula: C₄H₆O₅
• Color/Form: Neat
• InChI: InChI=1S/C4H6O5/c5-3(6)1-9-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
• InChI key: InChIKey=QEVGZEDELICMKH-UHFFFAOYSA-N
• SMILES: O=C(O)COCC(=O)O