Product Information
Name:Dihydroberberine
Controlled Product
Synonyms:
- 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine
- 5,8-dihydro-9,10-dimethoxy-
- Berberine
- dihydro- (6CI,7CI)
- Berbine
- 13,13a-didehydro-9,10-dimethoxy-2,3-(methylenedioxy)- (8CI)
- 7,8-Dihydroberberine
- Dihydroumbellatine
- NSC 331264
Brand:TRC
Description:
Applications Dihydroberberine is a derivative Berberine (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:337.369
Formula:C20H19NO4
Color/Form:Neat
InChI:InChI=1S/C20H19NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-9H,5-6,10-11H2,1-2H3
InChI key:InChIKey=FZAGOOYMTPGPGF-UHFFFAOYSA-N
SMILES:COc1ccc2c(c1OC)CN1CCc3cc4c(cc3C1=C2)OCO4
Technical inquiry about: Dihydroberberine
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