N6-[(1,1-Dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-lysine

CAS: 92122-45-7

Ref. TR-D447255

Product Information

• Name: N6-[(1,1-Dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-lysine
• Synonyms: (R)-6-[(tert-Butoxycarbonyl)amino]-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]hexanoic Acid, Fmoc-D-Lys(Boc)-OH, Nalpha-Fmoc-Nepsilon-Boc-D-lysine
• Brand: TRC

Description

Applications Derivative of N6-​[(1,​1-​Dimethylethoxy)​carbonyl]​-​N2-​[(9H-​fluoren-​9-​ylmethoxy)​carbonyl]​-D-​lysine is a hetero-bifunctional traceless linker for temporarily attaching highly solubilizing peptide sequences onto insoluble peptides.
References Jacobsen, M., et al.: J. Am. Chem. Soc., 138, 11775-11782 (2016)

Chemical properties

• Molecular weight: 468.54
• Formula: C₂₆H₃₂N₂O₆
• Color/Form: Neat
• InChI: InChI=1S/C26H32N2O6/c1-26(2,3)34-24(31)27-15-9-8-14-22(23(29)30)28-25(32)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30)/t22-/m1/s1
• InChI key: InChIKey=UMRUUWFGLGNQLI-JOCHJYFZSA-N
• SMILES: CC(C)(C)OC(=O)NCCCC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O