Dihydro Artemisinin-13C,d4

CAS: 71939-50-9

Ref. TR-D448363

Product Information

• Name: Dihydro Artemisinin-13C,d4
• Synonyms: (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol-13C,d4, beta-Dihydroartemisinin-13C,d4, Alaxin-13C,d4, Cotecxin-13C,d4, Cotexin-13C,d4, DHQHS 2-13C,d4, Dihydroartemisinine-13C,d4, Dihydroqinghaosu-13C,d4, (3R,5aS,6R,8aS,9R,10R,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol, (3R,5aS,6R,8aS,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol, (3R,5aS,6R,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol, (5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol, (5aS,6R,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol, 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol, decahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-, 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol, decahydro-3,6,9-trimethyl-, [3R-(3α,5aβ,6β,8aβ,9α,10α,12β,12aR*)]-, Alaxin, Artemisinin deriv. DHA, Artenimol, Cid 3000518, Cotecxin, Cotexin, Dhqhs 1, Dhqhs 2, Di-hydro artemisinin, Dihydroartemisinin, Dihydroartemisinine, Dihydroqinghaosu, Dynamax, Hc 101C, Salaxin, Santecxin, β-Dihydroartemisinin

Description

Applications The labelled analogue of the main metabolite of Artemisinin, Arteether, Artemether, Artesunate. An active antimalarial metabolite.
References de Vries, P., et al.: Drugs, 52, 818 (1996), Kamolrat, S., et al.: Antimicrob. Agents Chemother., 47, 3795 (2003), Mithwani, S., et al.: Br. J. Clin. Pharmacol., 57, 146 (2004),

• Brand: TRC

Chemical properties

• Molecular weight: 289.365
• Formula: CC₁₄D₄H₂₀O₅
• Color/Form: Neat
• InChI: InChI=1S/C15H24O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-13,16H,4-7H2,1-3H3/t8-,9-,10+,11+,12+,13-,14-,15-/m1/s1/i2+1D3,12D
• InChI key: InChIKey=BJDCWCLMFKKGEE-QJASMAIJSA-N
• SMILES: [2H][C@]1(O)O[C@@H]2O[C@@]3(C)CC[C@H]4[C@H](C)CC[C@@H]([C@H]1[13C]([2H])([2H])[2H])[C@]42OO3