1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride

CAS: 70918-74-0

Ref. TR-D448445

Product Information

• Name: 1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride
• Synonyms: Doxazosin Mesilate Imp. B (EP), Doxazosin USP Related Compound A, Doxazosin USP RC A, 1-[(2RS)-2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl]piperazine Hydrochloride, Doxazosin Mesilate Imp. B (EP) as Hydrochloride, Doxazosin Related Compound A as Hydrochloride, Doxazosin Mesilate Impurity B as Hydrochloride, Doxazosin Impurity B as Hydrochloride, (2,3-Dihydro-BENZO[1,4]DIOXIN-2-YL)-PIPERAZIN-1-YL-METHANONE HYDROCHLORIDE, (2,3-Dihydro-BENZO[1,4]DIOXIN-2-YL)PIPERAZINE-1-YL-METHANONE HYDROCHLORIDE, 1,4-Benzodioxin, piperazine deriv., 1,4-benzodioxan-2-CARBONYL PIPERAZINE HCL, 1-(1,4-benzodioxane-2-CARBONYL)PIPERAZINE HYDROCHLORIDE, 1-(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)piperazine hydrochloride, 4-(2,3-Dihydro-1,4-Benzodioxin-2-Ylcarbonyl)Piperazin-1-Ium Chloride, Methanone, (2,3-dihydro-1,4-benzodioxin-2-yl)-1-piperazinyl-, hydrochloride (1:1), N-(1,4-Benzodioxane-2-carbonyl)piperazine Hydrochloride, N-(1,4-benzodioxan-2-CARBONYL)-PIPERAZINE HCL, N-[(1, 4-Benzodioxane-2-yl)carbonyl]piperazine hydrochloride, N-[(1,4-Benzodioxane-2-yl)carbonyl]piperazine HCl, N-[(1,4-Benzodioxane-2-yl)carbonyl]piperazine hydrochloride, N-[(1,4-Benzodioxane-2-yl)carboxyl] piperazine hydrochloride, Piperazine, 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, monohydrochloride, Timtec-Bb Sbb003004

Description

Impurity Doxazosin EP Impurity B
Stability Hygroscopic
Applications 1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride (Doxazosin EP Impurity B) is an impurity of Doxazosin (D537500), a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982), de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982),

• Brand: TRC

Chemical properties

• Molecular weight: 284.74
• Formula: C₁₃H₁₆N₂O₃·ClH
• Color/Form: Neat
• InChI: /h1-4,12,14H,5-9H2, 1H, InChI=1S/C13H16N2O3.ClH/c16-13(15-7-5-14-6-8-15)12-9-17-10-3-1-2-4-11(10)18-12
• InChI key: InChIKey=TUKBWYXLYINULI-UHFFFAOYSA-N
• SMILES: Cl.O=C(C1COc2ccccc2O1)N1CCNCC1