7,8-Dihydro-L-Biopterin-d3

CAS: 1217782-44-9

Ref. TR-D448552

Product Information

• Name: 7,8-Dihydro-L-Biopterin-d3
• Synonyms: 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone, 7,8-Dihydrobiopterin, Dihydrobiopterin, L-erythro-7,8-Dihydrobiopterin, L-erythro-Dihydrobiopterin

Description

Applications The labelled reduced form of Biopterin. An oxidation product of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 µM.
References Shen, R., et al.: Biochim Biophys Acta., 965, 9 (1988), Kwon, N.S., et al.: J. Biol. Chem., 264, 20498 (1989), Werner, E.R., et al.: Proc. Soc. Exp. Biol. Med., 203, 1 (1993),

• Brand: TRC

Chemical properties

• Molecular weight: 242.25
• Formula: C₉H₁₀D₃N₅O₃
• Color/Form: Neat
• InChI: InChI=1S/C9H13N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,6,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,6-/m0/s1/i1D3
• InChI key: InChIKey=FEMXZDUTFRTWPE-OERXLRDQSA-N
• SMILES: [2H]C([2H])([2H])[C@H](O)[C@H](O)C1=Nc2c([nH]c(N)nc2=O)NC1