Dihydro Finasteride

CAS: 98319-24-5

Ref. TR-D448975

Product Information

• Name: Dihydro Finasteride
• Synonyms: N-(1,1-Dimethylethyl)-3-oxo-4-aza-5alpha-androstane-17beta-carboxamide, Finasteride Imp. A (EP), Dihydrofinasteride, 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-(1,1-dimethylethyl)hexadecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-, 4-Azaandrostane-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5α,17β)-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(1,1-Dimethylethyl)hexadecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide, 1,2-Dihydrofinasteride, 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-(1,1-dimethylethyl)hexadecahydro-4a,6a-dimethyl-2-oxo-, [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)]-, 3-Oxo-4-aza-5α-androstan-17β-carboxylic acid N-(tert-butyl)amide, N-(tert-Butyl)-3-oxo-4-aza-5α-androstane-17-carboxamide, N-(tert-Butyl)-3-oxo-4-aza-5α-androstane-17β-carboxamide, Finasteride Impurity A, 17β-(N-tert-Butylcarbamoyl)-4-aza-5α-androstan-3-one, 3-Oxo-4-Aza-5A-Androstane-17B-(N-T-Butyl)Carboxamide, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-tert-butyl-4a,6a-dimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide, Androstane-N-terbutyl-3-oxo-4-aza-5 alfa-17 beta-carboxamide, 17-Beta-(N-Butylcarbamoyl)-4-Aza-5-Alpha-Androstan-3-One, 17β-(t-Butylcarbamoyl)-4-aza-5a-androstan-3-one, Dihydroproscar, N-tert-butyl-3-oxo-4-aza-5α-androst-17β-carboxamide
• CAS: 98319-24-5

Description

Impurity Finasteride EP Impurity A
Applications Dihydro Finasteride (Finasteride EP Impurity A) is the reduced product of Finasteride (F342000): a mechanism-based inhibitor of human prostate and skin steroid 5α-reductase. It forms an enzyme-bound NADP-dihydrofinasteride adduct during this inhibitory process.
References Bull, H.G. et al.: Am. J. Chem. Soc., 118, 2359 (1996); Liang, T. et al.: Endocrinol., 117, 571 (1985); Ellsworth, K.P. et al.: J. Steroid Bioche. Mol. Biol., 66, 271 (1998);

• Brand: TRC

Chemical properties

• Molecular weight: 374.56
• Formula: C₂₃H₃₈N₂O₂
• Color/Form: Off-White
• InChI: InChI=1S/C23H38N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h14-18H,6-13H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
• InChI key: InChIKey=ZOIUUCNFVDJSJK-WSBQPABSSA-N
• SMILES: CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C