[4S-(4a,7b,7aa)]-7,7a-Dihydro-7-hydroxy-4-methoxy-4H-furo[3,2-c]pyran-2(6H)-one-13C3

CAS: 123251-08-1

Ref. TR-D449413

Product Information

• Name: [4S-(4a,7b,7aa)]-7,7a-Dihydro-7-hydroxy-4-methoxy-4H-furo[3,2-c]pyran-2(6H)-one-13C3
• Synonyms: (4S,7S)-7-hydroxy-4-methoxy-7,7a-dihydro-4H-furo[4,5-c]pyran-2(6H)-one-2,3,4-13C3
• Brand: TRC

Description

Applications [4S-(4α,7β,7aα)]-7,7a-Dihydro-7-hydroxy-4-methoxy-4H-furo[3,2-c]pyran-2(6H)-one-13C3 is an intermediate used in the synthesis of Patulin-13C3 (P206502), which is a labelled Patulin (PAT), a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. Patulin-induced genotoxicity and modulation of glutathione in Hep G2 cells. Antibiotic.
References Scott, P., et al.: J. Agric. Food Chem., 20, 450 (1972), Aden, D., et al.: Nature, 282, 615 (1979), Surralles, J., et al.: Mutat. Res., 341, 169 (1995), Alves, I., et al.: Mutagenesis, 15, 229 (2000), Liu, B., et al.: Toxicol. Appl. Pharmacol., 191, 255 (2003)

Chemical properties

• Molecular weight: 189.14
• Formula: C₅C₃H₁₀O₅
• Color/Form: Neat
• InChI: InChI=1S/C8H10O5/c1-11-8-4-2-6(10)13-7(4)5(9)3-12-8/h2,5,7-9H,3H2,1H3/t5-,7?,8-/m0/s1/i2+1,6+1,8+1
• InChI key: InChIKey=VFVYCHOMLNCURP-SXZSISPLSA-N
• SMILES: CO[13C@H]1OC[C@H](O)C2O[13C](=O)[13CH]=C21