Dihydro Uracil-d4

CAS: 334473-41-5

Ref. TR-D449993

Product Information

• Name: Dihydro Uracil-d4
• Synonyms: 5,6-Dihydrouracil-d4,2,4(1H,3H)-Pyrimidinedione-5,6-d2, dihydro-d2- (9CI), Dihydro-d2-2,4(1H,3H)-pyrimidinedione-5,6-d2, Hydrouracil-d4, 5,6-Dihydro-2,4(1H,3H)-pyrimidinedione-5,5,6,6-d4, 5,6-Dihydro-2,4-dihydroxypyrimidine-5,5,6,6-d4, 5,6-Dihydrouracil-5,5,6,6-D4, Dihydrouracil-d4

Description

Applications Dihydro uracil-d4 is deuterium labelled dihydro uracil (D449990). Modified nucleobases are useful molecular tools to study nucleic acid structures and to probe biological systems. Dihydro uracil has also been utilized in mechanistic studies relating to the base excision repair (BER) pathway during DNA repair.
References Chawla, M., et al.: Nucleic Acids Res 43, 9573 (2015); Jian, Y., et al.: J. Am. Chem. Soc. 137, 3318 (2015); Shaul, Y. D., et al.: Cell 158, 1094 (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 118.13
• Formula: C₄H₂D₄N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C4H6N2O2/c7-3-1-2-5-4(8)6-3/h1-2H2,(H2,5,6,7,8)/i1D2,2D2
• InChI key: InChIKey=OIVLITBTBDPEFK-LNLMKGTHSA-N
• SMILES: [2H]C1([2H])NC(=O)NC(=O)C1([2H])[2H]