(RS)-3,5-DHPG

CAS: 146255-66-5

Ref. TR-D450028

Product Information

• Name: (RS)-3,5-DHPG
• Synonyms: alpha-Amino-3,5-dihydroxybenzeneacetic Acid, (RS)-3,5-Dihydroxyphenylglycine, (±)-alpha-Amino-3,5-dihydroxybenzeneacetic Acid, 3,5-Dihydroxyphenylglycine, DHPG, DL-2-(3,5-Dihydroxyphenyl)glycine, (D/L)-3,5-Dihydroxyphenylglycine, 2-Amino-2-(3,5-dihydroxyphenyl)acetic Acid, (2S)-amino(3,5-dihydroxyphenyl)ethanoic acid, (<span class="text-smallcaps">D</smallcap>/<smallcap>L</span>)-3,5-Dihydroxyphenylglycine, (Rs)-3,5-Dihydroxyphenylglycine, (±)-α-Amino-3,5-dihydroxybenzeneacetic acid, 2-Amino-2-(3,5-dihydroxyphenyl)acetic acid, <span class="text-smallcaps">D</smallcap><smallcap>L</span>-2-(3,5-Dihydroxyphenyl)glycine, Amino(3,5-Dihydroxyphenyl)Acetic Acid, Benzeneacetic acid, α-amino-3,5-dihydroxy-, Dl-Alpha-(3,5-Dihydroxyphenyl)Glycine, N-(3,5-dihydroxyphenyl)glycine

Description

Applications (RS)-3,5-DHPG is a selective group I metabotropic glutamate receptor agonist which activates both mGluR1 and mGluR5. It has been shown that (RS)-3,5-DHPG can modulate Kir4.1 protein and mRNA in cultured rat retinal Müller cells.(RS)-3,5-DHPG acts as a potential target in treatment of parkinson's disease.
References (1) Gao, F., et al.: Neurosci Lett. 588, 12 (2015)

• Brand: TRC

Chemical properties

• Molecular weight: 183.16
• Formula: C₈H₉NO₄
• Color/Form: Neat
• InChI: InChI=1S/C8H9NO4/c9-7(8(12)13)4-1-5(10)3-6(11)2-4/h1-3,7,10-11H,9H2,(H,12,13)
• InChI key: InChIKey=HOOWCUZPEFNHDT-UHFFFAOYSA-N
• SMILES: NC(C(=O)O)c1cc(O)cc(O)c1