(E)-N-[2-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)ethyl]acetamide(Agomelatine Impurity)

CAS: 178677-39-9

Ref. TR-D450485

Product Information

• Name: (E)-N-[2-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)ethyl]acetamide(Agomelatine Impurity)
• Synonyms: N-[(2E)-2-(7-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)ethyl]acetamide

Description

Impurity Agomelatine Impurity 2
Stability Light Sensitive
Applications (E)-N-[2-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)ethyl]acetamide is an impurity of Agomelatine (A430000) which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors and used in the treatment of major depressive disorder. Agomelatine Impurity 2
References Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003),

• Brand: TRC

Chemical properties

• Molecular weight: 245.317
• Formula: C₁₅H₁₉NO₂
• Color/Form: Neat
• InChI: InChI=1S/C15H19NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h6-8,10H,3-5,9H2,1-2H3,(H,16,17)/b13-8+
• InChI key: InChIKey=WYDPNFMLFHAFHV-MDWZMJQESA-N
• SMILES: COc1ccc2c(c1)/C(=C/CNC(C)=O)CCC2