(3b,5a,16b)-3,17-Dihydroxy-16-methylpregnan-20-one

CAS: 2543-24-0

Ref. TR-D450509

Product Information

• Name: (3b,5a,16b)-3,17-Dihydroxy-16-methylpregnan-20-one
• Synonyms: 3beta,17-Dihydroxy-16beta-methyl-5alpha-pregnan-20-one
• Brand: TRC

Description

Applications (3β,5α,16β)-3,17-Dihydroxy-16-methylpregnan-20-one is an intermediate used in the synthesis of (16β)-21-(Acetyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione (A187753), which is a useful intermediate that is used in the synthetic preparation of methylhydroxypregnendione via epoxidation, Grignard addition., and oxidation.
References Tian, W.; et al.: Faming Zhuanli Shenqing 18pp. Patent 2011 CODEN:CNXXEV

Chemical properties

• Molecular weight: 348.52
• Formula: C₂₂H₃₆O₃
• Color/Form: Neat
• InChI: InChI=1S/C22H36O3/c1-13-11-19-17-6-5-15-12-16(24)7-9-20(15,3)18(17)8-10-21(19,4)22(13,25)14(2)23/h13,15-19,24-25H,5-12H2,1-4H3/t13-,15-,16-,17+,18-,19-,20-,21-,22-/m0/s1
• InChI key: InChIKey=RGHGKGRVFXQGOV-RKCQDTMWSA-N
• SMILES: CC(=O)[C@@]1(O)[C@@H](C)C[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C