2,5-Difluorobenzoic Acid

CAS: 2991-28-8

Ref. TR-D451183

Product Information

• Name: 2,5-Difluorobenzoic Acid
• Synonyms: NSC 190310, 2,3-Dichloro benzoic acid, 2,5-Difluorobenzic acid, 2,5-Difluorobenzoate, 2,5-Difluorobenzoicacid, Benzoic acid, 2,5-difluoro-, Rarechem Al Bo 0019

Description

Applications 2,5-Difluorobenzoic Acid acts as a reagent in the synthesis of rutaecarpine and analogs used for the removal of caffeine from the body. Prepparation of quinolone carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase (Erratum). Preparation, molecular docking, and bioactivity of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis. Also used as new passive water tracers for oil field applications.
References Liang, L., et al.: Tetrahedron Lett., 56, 2466 (2015); Zhi, Y., et al.: Bioorg. Med. Chem., 22, 4347 (2014); Serres-P, C., et al.: Energy & Fuels, 25, 4488 (2011); Chen, J., et al.: J. Med. Chem., 53, 4545 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 158.1
• Formula: C₇H₄F₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C7H4F2O2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,(H,10,11)
• InChI key: InChIKey=LBQMIAVIGLLBGW-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(F)ccc1F