Dihydronarwedine

CAS: 21041-10-1

Ref. TR-D453580

Product Information

• Name: Dihydronarwedine
• Synonyms: 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-one, 4a,5,7,8,9,10,11,12-octahydro-3-methoxy-11-methyl-, (4aS,8aR)-, Galanthamine, 3-deoxy-1,2-dihydro-3-oxo- (9CI), Lycoramine, 2-deoxy-2-oxo- (8CI), Lycoramine, deoxyoxo- (7CI), (4aS,8aR)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one, 6H-Benzofuro[3a,3,2-ef][2]benzazepine, galanthamine deriv., (-)-Dihydrogalanthaminone, (-)-Lycoraminone

Description

Applications Dihydronarwedine is a metabolite of Galanthamine (G188500), a selective acetylcholinesterase inhibitor and therapeutic agent for the treatment and prevention of Alzheimer’s disease and disorders resulting from reduced neuronal metabolism.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koizumi, J., et al.: Chem. Pharma. Bull., 12, 696 (1964); Friess, S.L., et al.: Toxicol. Appl. Pharmacol., 3, 347 (1961); Bickel, U., et al.: Clin. Pharmacol. Ther., 50, 420 (1991); Harvey, A.L., et al.: Pharmacol. Ther., 68, 113 (1995)

• Brand: TRC

Chemical properties

• Molecular weight: 287.35
• Formula: C₁₇H₂₁NO₃
• Color/Form: Neat
• InChI: InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-4,14H,5-10H2,1-2H3/t14-,17-/m0/s1
• InChI key: InChIKey=UFQNQEIAGBZCBL-YOEHRIQHSA-N
• SMILES: COc1ccc2c3c1O[C@H]1CC(=O)CC[C@@]31CCN(C)C2