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10,17β-Dihydroxy-estra-1,4-dien-3-one

CAS:

Ref. TR-D454120

25mg
1,022.00€
10,17β-Dihydroxy-estra-1,4-dien-3-one
TRC

    Product Information

    Name:10,17β-Dihydroxy-estra-1,4-dien-3-one
    Controlled Product
    Synonyms:
    • 10,17beta-Dihydroxy-estra-1,4-dien-3-one
    • 17β-Hydroxy-p-estraquinol
    • DHED
    Brand:TRC
    Description:Applications 10,17β-Dihydroxy-estra-1,4-dien-3-one is a prodrug that can be converted to the main human estrogen, 17β-estradiol, in the brain and not elsewhere in the body due to an enzyme expressed only in the brain. It provides positive estrogenic effects on the brain and relieve symptoms in patients with a broad range of central nervous system diseases without side effects in other tissues.References Prokai, L., et al.: Sci. Transl. Med., 7, 297 (2015)
    Notice:Our products are intended for lab use only. For any other use, please contact us.

    Chemical properties

    Molecular weight:288.381
    Formula:C18H24O3
    Color/Form:Neat
    InChI:InChI=1S/C18H24O3/c1-17-8-7-15-13(14(17)4-5-16(17)20)3-2-11-10-12(19)6-9-18(11,15)21/h6,9-10,13-16,20-21H,2-5,7-8H2,1H3/t13-,14-,15-,16-,17-,18+/m0/s1
    InChI key:InChIKey=UIKDFTLKOKNUJP-UHFFFAOYSA-N
    SMILES:CC12CCC3C(CCC4=CC(=O)C=CC43O)C1CCC2O

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