Diisopropyl Carbonate (Stabilized with Calcium Carbonate)

CAS: 6482-34-4

Ref. TR-D455500

Product Information

• Name: Diisopropyl Carbonate (Stabilized with Calcium Carbonate)
• Synonyms: Carbonic Acid Diisopropyl Ester, Bis-2-propyl Carbonate, Diisopropyl Carbonate, Bis-2-propyl carbonate, Carbonic acid bis(1-methylethyl) ester, Dipropan-2-Yl Carbonate, 2-Tert-Butyl-1-[2-(4-Methoxyphenoxy)Ethoxy]-4-Methylbenzene

Description

Applications Diisopropyl Carbonate is used in the synthesis of Huperizine A (H826000) a reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. A potential therapeutic agent for Alzheimer’s disease. It reduces cell death induced by glutamate in primary cultures derived from forebrain, hippocampus, cortex and cerebellum of embryonic rat brain.
References Ding, X. et al.: Tetrahedron 68, 6240 (2012); Wang, Y.-E., et al.: Acta Pharmacol. Sin., 7, 110 (1986), Ved, H.S., et al.: Neuroreport, 8, 963 (1997)

• Brand: TRC

Chemical properties

• Molecular weight: 146.18
• Formula: C₇H₁₄O₃
• Color/Form: Neat
• InChI: InChI=1S/C7H14O3/c1-5(2)9-7(8)10-6(3)4/h5-6H,1-4H3
• InChI key: InChIKey=JMPVESVJOFYWTB-UHFFFAOYSA-N
• SMILES: CC(C)OC(=O)OC(C)C