Dimesna

CAS: 16208-51-8

Ref. TR-D460660

Product Information

• Name: Dimesna
• Synonyms: 2,2'-Dithiobis-ethanesulfonic Acid Sodium Salt (1:2), Ethanesulfonic acid, 2,2'-dithiobis-, disodium salt (9CI), Ethanesulfonic acid, 2,2'-dithiodi-, disodium salt (6CI,8CI), 2,2'-Dithiodi-1-ethanesulfonic acid disodium salt, BNP 7787, Bis(2-sulfoethyl)disulfide disodium salt, Disodium 2,2'-dithiobis(ethanesulfonate), Disodium 2,2'-dithiodiethanesulfonate, NSC 716976, Tavocept, 16208-51-8, 2,2′-Dithiodi-1-ethanesulfonic acid disodium salt, Bnp 7787, Disodium 2,2'-disulfanediyldiethanesulfonate, Disodium 2,2′-dithiobis(ethanesulfonate), Disodium 2,2′-dithiodiethanesulfonate, Ethanesulfonic Acid, 2,2'-Dithiobis-, Sodium Salt (1:2), Ethanesulfonic acid, 2,2′-dithiobis-, disodium salt, Ethanesulfonic acid, 2,2′-dithiodi-, disodium salt

Description

Impurity Mesna EP Impurity D
Applications Dimesna (Mesna EP Impurity D) reacts with acrolein and other urotoxic metabolites of oxazaphosphorines (cyclophosphamide or ifosfamide) to form stable, non-urotoxic compounds. Mesna does not have any antitumour activity, nor does it appear to interfere with the antitumour activity of antineoplastic drugs. This medication is used to protect the bladder wall from the harmful effects of some cancer-fighting drugs.
References Yang, C., et al.: J. Biol. Chem., 262, 3086 (1987), Boven, E., et al.: Eur. J. Cancer, 38, 1148 (2002), Verschraagen, M., et al.: Clin. Pharmacol. Ther., 74, 157 (2003),

• Brand: TRC

Chemical properties

• Molecular weight: 326.34
• Formula: C₄H₈O₆S₄Na
• Color/Form: White To Off-White
• InChI: InChI=1S/C4H10O6S4.2Na/c5-13(6,7)3-1-11-12-2-4-14(8,9)10;;/h1-4H2,(H,5,6,7)(H,8,9,10);;/q;2*+1/p-2
• SMILES: O=S(=O)([O-])CCSSCCS(=O)(=O)[O-].[Na+].[Na+]