Dimesna

CAS: 16208-51-8

Ref. TR-D460660

Product Information

• Name: Dimesna
• Synonyms: 2,2'-Dithiobis-ethanesulfonic Acid Sodium Salt (1:2), Ethanesulfonic acid, 2,2'-dithiobis-, disodium salt (9CI), Ethanesulfonic acid, 2,2'-dithiodi-, disodium salt (6CI,8CI), 2,2'-Dithiodi-1-ethanesulfonic acid disodium salt, BNP 7787, Bis(2-sulfoethyl)disulfide disodium salt, Disodium 2,2'-dithiobis(ethanesulfonate), Disodium 2,2'-dithiodiethanesulfonate, NSC 716976
• Brand: TRC
• Description: Impurity Mesna EP Impurity DApplications Dimesna (Mesna EP Impurity D) reacts with acrolein and other urotoxic metabolites of oxazaphosphorines (cyclophosphamide or ifosfamide) to form stable, non-urotoxic compounds. Mesna does not have any antitumour activity, nor does it appear to interfere with the antitumour activity of antineoplastic drugs. This medication is used to protect the bladder wall from the harmful effects of some cancer-fighting drugs.References Yang, C., et al.: J. Biol. Chem., 262, 3086 (1987), Boven, E., et al.: Eur. J. Cancer, 38, 1148 (2002), Verschraagen, M., et al.: Clin. Pharmacol. Ther., 74, 157 (2003),

Chemical properties

• Molecular weight: 326.34
• Formula: C₄H₈O₆S₄·2Na
• Color/Form: White To Off-White
• InChI: InChI=1S/C4H10O6S4.2Na/c5-13(6,7)3-1-11-12-2-4-14(8,9)10;;/h1-4H2,(H,5,6,7)(H,8,9,10);;/q;2*+1/p-2
• SMILES: O=S(=O)([O-])CCSSCCS(=O)(=O)[O-].[Na+].[Na+]