1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarboxamide

CAS: 64372-56-1

Ref. TR-D461420

Product Information

• Name: 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarboxamide
• Synonyms: (1RS)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carboxamide, Citalopram-Amide,5-Isobenzofurancarboxamide, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, Citalopram Hydrobromide Imp. A (EP)
• Brand: TRC
• Description: Impurity Escitalopram EP Impurity A/ USP Citalopram Related Compound AApplications 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarboxamide (Escitalopram EP Impurity A), is an impurity of Citalopram (C505000), which is an inhibitor of serotonin (5-HT) uptake. It is used as an antidepressant.References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001)

Chemical properties

• Molecular weight: 342.41
• Formula: C₂₀H₂₃FN₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C20H23FN2O2/c1-23(2)11-3-10-20(16-5-7-17(21)8-6-16)18-9-4-14(19(22)24)12-15(18)13-25-20/h4-9,12H,3,10-11,13H2,1-2H3,(H2,22,24)
• InChI key: InChIKey=LYYWQJNKWCANAC-FQEVSTJZSA-N
• SMILES: CN(C)CCC[C@@]1(c2ccc(F)cc2)OCc2cc(C(N)=O)ccc21