Des[9-((3R,4R)-3-Methoxy-4-Hydroxy-cyclohexyl)-(1R,4R,8R)-2,4,8-Trimethyl-1-Hydroxy-5-Oxo-nona-2,6-dien-1-yl] seco Rapamycin

CAS:
147438-30-0

Ref. TR-D461585

25mg

1,530.00€

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Product Information

Name:Des[9-((3R,4R)-3-Methoxy-4-Hydroxy-cyclohexyl)-(1R,4R,8R)-2,4,8-Trimethyl-1-Hydroxy-5-Oxo-nona-2,6-dien-1-yl] seco Rapamycin

Controlled Product

Synonyms:

Everolimus Related Compound 3

Brand:TRC

Description:Applications (2S)-1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrien-1-yl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]-2-oxoacetyl]-2-piperidinecarboxylic Acid is an impurity of Sirolimus (R124000) which is an immunosuppressant drug used to prevent rejection in organ transplantation.References Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004)

Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:591.73

Formula:C₃₂H₄₉NO₉

Color/Form:Neat

InChI:InChI=1S/C32H49NO9/c1-21(18-23(3)27(34)20-40-5)12-8-7-9-13-22(2)28(41-6)19-25-16-15-24(4)32(39,42-25)29(35)30(36)33-17-11-10-14-26(33)31(37)38/h7-9,12-13,21,23-26,28,39H,10-11,14-20H2,1-6H3,(H,37,38)/b9-7+,12-8+,22-13+/t21-,23-,24-,25+,26+,28+,32-/m1/s1

SMILES:CSc1nc(NC2CCCC2)c([N+](=O)[O-])c(NC2CCCC2)n1

Technical inquiry about: Des[9-((3R,4R)-3-Methoxy-4-Hydroxy-cyclohexyl)-(1R,4R,8R)-2,4,8-Trimethyl-1-Hydroxy-5-Oxo-nona-2,6-dien-1-yl] seco Rapamycin

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