N-(2,6-Dimethylphenyl)-3-methyl-2-butenamide

CAS: 71352-89-1

Ref. TR-D465630

Product Information

• Name: N-(2,6-Dimethylphenyl)-3-methyl-2-butenamide
• Synonyms: 2',6'-Senecioxylidide
• Brand: TRC
• Description: Applications N-(2,6-Dimethylphenyl)-3-methyl-2-butenamide is an intermediate in the synthesis of rac-trans-N-(2,6-Dimethylphenyl)-4-methyl-1-(2-methylphenyl)-5-oxo-3-propylimidazolidine-2-carboxamide (D480822), the trans-isomer of N-(2,6-Dimethylphenyl)-4-methyl-1-(2-methylphenyl)-5-oxo-3-propylimidazolidine-2-carboxamide, an impurity of Prilocaine (Prilocaine Hydrochloride P725000). Prilocaine is a local anesthetic of the amino amide type and is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA) towards the treatment of conditions like paresthesia.References Caliaro, G., et al.: J. Pharm. Biomed. Anal., 26, 427 (2001), Ulmeanu, S., et al.: Pharm. Res., 20, 1317 (2003),

Chemical properties

• Molecular weight: 203.28
• Formula: C₁₃H₁₇NO
• Color/Form: Neat
• InChI: InChI=1S/C13H17NO/c1-9(2)8-12(15)14-13-10(3)6-5-7-11(13)4/h5-8H,1-4H3,(H,14,15)
• InChI key: InChIKey=UKGBGOCRBIGFAE-UHFFFAOYSA-N
• SMILES: CC(C)=CC(=O)Nc1c(C)cccc1C