(AlphaR)-Alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]benzeneacetic Acid

CAS: 1286280-61-2

Ref. TR-D469610

Product Information

• Name: (AlphaR)-Alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]benzeneacetic Acid
• Synonyms: (R)-2-((tert-butoxycarbonyl)amino)-2-(4-((tert-butyldimethylsilyl)oxy)phenyl)acetic acid
• Brand: TRC

Description

Applications (αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]benzeneacetic Acid is an impurity in the synthesis of Cefprozil (C243910), semisynthetic oral cephalosporin consisting of approx. 90:10 Z/E isomeric mixture. Antibacterial.
References Jones, R.N., et al.: Diagn. Microb. Infect. Dis., 9, 11 (1988), Barbhaiya, R.H., et al.: Antimicrob. Agents Chemother., 34, 1204 (1990)

Chemical properties

• Molecular weight: 381.54
• Formula: C₁₉H₃₁NO₅Si
• Color/Form: Neat
• InChI: InChI=1S/C19H31NO5Si/c1-18(2,3)24-17(23)20-15(16(21)22)13-9-11-14(12-10-13)25-26(7,8)19(4,5)6/h9-12,15H,1-8H3,(H,20,23)(H,21,22)/t15-/m1/s1
• InChI key: InChIKey=GKSNEUMZNDKSTN-VQVTYTSYSA-N
• SMILES: COC(=O)[C@@H](O)[C@H]1OC(C)(C)O[C@@H]1CO