Product Information
- 3-Amino-N-(aminoiminomethyl)-6-chloro-5-(dimethylamino)-pyrazinecarboxamide-d6 Monohydrochloride
- N-Amidino-3-amino-6-chloro-5-(dimethylamino)-pyrazinecarboxamide-d6 Monohydrochloride
- (3-Amino-5-dimethylamino-6-chloropyrazinoyl)guanidine-d6 Hydrochloride
- Pyrazinecarboxamide,3-amino-N-(aminoiminomethyl)-6-chloro-5-(dimethylamino)-, monohydrochloride(9CI)
- Pyrazinecarboxamide, N-amidino-3-amino-6-chloro-5-(dimethylamino)-,monohydrochloride (8CI)
- (3-Amino-5-dimethylamino-6-chloropyrazinoyl)guanidinehydrochloride
Applications 5-(N,N-Dimethyl)-amiloride-d6 Hydrochloride is an isotopic analog of 5-(N,N-Dimethyl)-amiloride Hydrochloride (D470570), which has been used to investigate biochemical processes related to the circadian clock in mouse and human cell lines. It can also inhibit sodium-hydrogen exchangers (NHE). NHEs regulate sodium and pH in various tissues.
References Isojima, Y., et al.: Proc. Natl. Acad. Sci. USA 106, 15744 (2009); Masereel, B., et al.: Eur J Med Chem 38, 547 (2003)
Chemical properties
Technical inquiry about: TR-D470572 5-(N,N-Dimethyl)-amiloride-d6 Hydrochloride
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