3-β-[N-(N’,N’-Dimethylaminoethane)-carbamoyl]cholesterol

CAS: 137056-72-5

Ref. TR-D470585

Product Information

• Name: 3-β-[N-(N’,N’-Dimethylaminoethane)-carbamoyl]cholesterol
• Synonyms: Cholesteryl N-(2-dimethylaminoethyl)carbamate, 3β-[N-(N,N-Dimethylaminoethyl)amidoformyl]cholesterol, 3β-[N-[2-(N,N-Dimethylamino)ethyl]carbamoyl]cholesterol, 3β-[N-{2-(Dimethylamino)ethyl}carbamoyl]cholesterol, DC-Chol
• Brand: TRC
• Description: Applications 3-β-[N-(N’,N’-Dimethylaminoethane)-carbamoyl]cholesterol is a cationic liposome reagent. It has been investigated in cancer gene therapy and vaccine delivery system.References Goyal, K., et al.: J. Liposome Res., 5, 49 (1995); Christensen, D., et al.: Exp. Rev. Vac., 10, 513 (2011); Gao, X., et al.: Biochem. Biophys. Res. Comm., 179, 280 (1991)

Chemical properties

• Molecular weight: 500.8
• Formula: C₃₂H₅₆N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C32H56N2O2/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35)/t23-,25+,26+,27-,28+,29+,31+,32-/m1/s1
• InChI key: InChIKey=HIHOWBSBBDRPDW-PTHRTHQKSA-N
• SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(=O)NCCN(C)C)CC[C@]4(C)[C@H]3CC[C@@]21C