Product Information
- 2,2-Dimethylbutyric Acid Chloride
- 2,2-Dimethylbutyryl Chloride
- 2,2-Dimethylbutanoic acid chloride
- 2,2-Dimethylbutyl Chloride
- 2,2-Dimethylbutyric acid chloride
- 2,2-Dimethylbutyryl chloride
- Butanoyl chloride, 2,2-dimethyl-
- Butyryl chloride, 2,2-dimethyl-
Applications 2,2-Dimethylbutanoyl chloride is a reagent that is used in the synthesis of 4α,5-Dihydro Simvastatin (D450010). 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),
Chemical properties
Technical inquiry about: TR-D471465 2,2-Dimethylbutanoyl Chloride
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