α-(2,3-Dimethylphenyl)-α-methyl-1H-imidazole-5-methanol-d3

CAS: 86347-12-8

Ref. TR-D473782

Product Information

• Name: α-(2,3-Dimethylphenyl)-α-methyl-1H-imidazole-5-methanol-d3
• Synonyms: 2,2,2-trideuterio-1-(2,3-dimethylphenyl)-1-(1H-imidazol-5-yl)ethanol

Description

Applications α-(2,3-Dimethylphenyl)-α-methyl-1H-imidazole-5-methanol-d3 is the isotope labelled analog of α-(2,3-Dimethylphenyl)-α-methyl-1H-imidazole-5-methanol (D473780); a reagent in the synthesis of Medetomidine (M203250) which is an α2-adrenergic agonist. Also a sedative and analgesic.
References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996); Chen, W., et al.: Faming Zhuanli Shenqing. CN 101921234 A 20101222. Dec 22, 2010

• Brand: TRC

Chemical properties

• Molecular weight: 219.297
• Formula: C₁₃D₃H₁₃N₂O
• Color/Form: Neat
• InChI: InChI=1S/C13H16N2O/c1-9-5-4-6-11(10(9)2)13(3,16)12-7-14-8-15-12/h4-8,16H,1-3H3,(H,14,15)/i3D3
• InChI key: InChIKey=LBUFLYABQRDXQB-HPRDVNIFSA-N
• SMILES: [2H]C([2H])([2H])C(O)(c1cnc[nH]1)c1cccc(C)c1C