(2R)-2-(2,6-Dichlorophenoxy)-propanoic Acid Methyl Ester
CAS:
Ref. TR-D474678
25mg
1,022.00€
Product Information
Name:(2R)-2-(2,6-Dichlorophenoxy)-propanoic Acid Methyl Ester
Controlled Product
Synonyms:
- (R)-Methyl 2-(2,6-Dichlorophenoxy)propanoate
Brand:TRC
Description:Applications (2R)-2-(2,6-Dichlorophenoxy)-propanoic Acid Methyl Ester is an intermediate in the synthesis of (R)-Lofexidine (L469395), which is the R-enantiomer of Lofexidine. α2-Adrenoceptor agonist related structurally to Clonidine. Used in treatment of opioid withdrawal symptoms; antihypertensive.References Velly, J., et al.: J. Pharmacol., 8, 351 (1977); Jarrot, B., et al.: Biochem. Pharmacol., 28, 141 (1979); Birch, P., at al.: Brit. J. Pharmacol., 68, 107 (1980)
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Chemical properties
Molecular weight:249.091
Formula:C10H10Cl2O3
Color/Form:Neat
InChI:InChI=1S/C10H10Cl2O3/c1-6(10(13)14-2)15-9-7(11)4-3-5-8(9)12/h3-6H,1-2H3/t6-/m1/s1
InChI key:InChIKey=XYYWAIIUSAQRSP-ZCFIWIBFSA-N
SMILES:COC(=O)[C@@H](C)Oc1c(Cl)cccc1Cl
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