2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
CAS:
Ref. TR-D476930
1g
246.00€
10g
909.00€
25g
1,693.00€
- Quinazoline and Quinoline Derivatives
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)
Product Information
Name:2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
Controlled Product
Synonyms:
- 3H-Pyrazol-3-one
- 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-
- 1-(3,4-Dimethylphenyl)-3-methyl-3-pyrazolin-5-one
Brand:TRC
Description:Applications 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, is an impurity of Eltrombopag (E508000), which is agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),
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Chemical properties
Molecular weight:202.25
Formula:C12H14N2O
Color/Form:Neat
InChI:InChI=1S/C12H14N2O/c1-8-4-5-11(6-9(8)2)14-12(15)7-10(3)13-14/h4-7,13H,1-3H3
InChI key:InChIKey=HBWBJCSXUJIDGN-UHFFFAOYSA-N
SMILES:Cc1cc(=O)n(-c2ccc(C)c(C)c2)[nH]1
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