2,5-Dimethyl-3-(2-methylphenyl)-1-propylimidazolini-4-one Hydrochloride

CAS: 677029-53-7

Ref. TR-D477056

Product Information

• Name: 2,5-Dimethyl-3-(2-methylphenyl)-1-propylimidazolini-4-one Hydrochloride
• Synonyms: 4-Imidazolidinone, 2,5-dimethyl-3-(2-methylphenyl)-1-propyl-, hydrochloride (1:1) (ACI), 4-Imidazolidinone, 2,5-dimethyl-3-(2-methylphenyl)-1-propyl-, hydrochloride (1:1), 4-Imidazolidinone, 2,5-dimethyl-3-(2-methylphenyl)-1-propyl-, monohydrochloride (9CI), 2,5-Dimethyl-3-(2-methylphenyl)-1-propylimidazolidin-4-one hydrochloride

Description

Applications rac-trans-2,5-Dimethyl-3-(2-methylphenyl)-1-propylimidazolini-4-one Hydrochloride is the salt analogue of 2,5-Dimethyl-3-(2-methylphenyl)-1-propylimidazolini-4-one (D477055), an impurity of Prilocaine (Prilocaine Hydrochloride P725000). Prilocaine is a local anesthetic of the amino amide type and is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA) towards the treatment of conditions like paresthesia.
References Caliaro, G., et al.: J. Pharm. Biomed. Anal., 26, 427 (2001), Ulmeanu, S., et al.: Pharm. Res., 20, 1317 (2003)

• Brand: TRC

Chemical properties

• Molecular weight: 282.8089
• Formula: C₁₅H₂₂N₂O·HCl
• Color/Form: Neat
• InChI: InChI=1S/C15H22N2O.ClH/c1-5-10-16-12(3)15(18)17(13(16)4)14-9-7-6-8-11(14)2;/h6-9,12-13H,5,10H2,1-4H3;1H
• InChI key: InChIKey=SMFZDMNGNJNBPP-UHFFFAOYSA-N
• SMILES: CCCN1C(C)C(=O)N(c2ccccc2C)C1C.Cl