N’-[2-[2,4-(Dimethylphenyl)thio]phenyl] Vortioxetine

Ref. TR-D477790

Product Information

• Name: N’-[2-[2,4-(Dimethylphenyl)thio]phenyl] Vortioxetine
• Synonyms: N,N’-Bis[2-[(2,4-imethylphenyl)thio]phenyl]-piperazine, 1,4-Bis(2-((2,4-dimethylphenyl)thio)phenyl)piperazine
• Brand: TRC
• Description: Applications N’-[2-[2,4-Dimethylphenyl)thio]phenyl] Vortioxetine is an impurity of Vortioxetine (V766000, HBr salt) which is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)

Chemical properties

• Molecular weight: 510.76
• Formula: C₃₂H₃₄N₂S₂
• Color/Form: Neat
• InChI: InChI=1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3
• InChI key: InChIKey=SAADBVWGJQAEFS-UHFFFAOYSA-N
• SMILES: CCN(CC)CCN1C(=O)CN=C(c2ccccc2F)c2cc(Cl)ccc21