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2,5-Dimethylpyrazine

CAS:

Ref. TR-D478970

5g
81.00€
2,5-Dimethylpyrazine
TRC

Product Information

Name:2,5-Dimethylpyrazine
Synonyms:
  • NSC 49139
Brand:TRC
Description:Applications 2,5-Dimethylpyrazine is used as a reagent in the synthesis of bone-targeted proteasome inhibitors for multiple myeloma (MM). 2,5-Dimethylpyrazine is also used in the preparation of 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340); a degredation product of Clavulanic Acid (C563750) which is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.References Agyin, J.K., et al.: Bioorg. Med. Chem. Lett., 23, 6455 (2013); Reading, C. and Cole, M.: Antimicrob. Ag. Chemother., 11, 852 (1977); Ball, A.P., et al.: Lancet, 1, 620 (1980); Brogden, R.N., et al. Drugs, 22, 337 (1981); Haginaka, J. et al.: Chem. Pharm. Bull., 33, 218 (1985)
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Chemical properties

Molecular weight:108.14
Formula:C6H8N2
Color/Form:Neat
InChI:InChI=1S/C6H8N2/c1-5-3-8-6(2)4-7-5/h3-4H,1-2H3
InChI key:InChIKey=LCZUOKDVTBMCMX-UHFFFAOYSA-N
SMILES:Cc1cnc(C)cn1

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