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5,7-Dinitro-8-quinolinol

CAS:

Ref. TR-D480280

1g
323.00€
100mg
143.00€
500mg
207.00€
5,7-Dinitro-8-quinolinol
TRC

    Product Information

    Name:5,7-Dinitro-8-quinolinol
    Controlled Product
    Synonyms:
    • 5,7-Bis(hydroxyl[oxido]amino)-8-hydroxyquinoline
    • 5,7-Dinitro-8-hydroxyquinoline
    • 5,7-Dinitrooxine
    • 8-Hydroxy-5,7-dinitroquinoline
    • NSC 57103
    • NSC 74940
    Brand:TRC
    Description:Applications 5,7-Dinitro-8-quinolinol is a useful synthetic intermediate. It has been reported that 5,7-dinitro-8-hydroxyquinoline derivatives exhibit higher antimycobacterial activity than ciprofloxacin (C482500) against M. abscessus and M. Smegmatis. In addition, 5,7-Dinitro-8-quinolinol has been employed to investigate structure-activity relationships of nitroxoline derivatives that may provide new insights on developing novel cathepsin B inhibitors.References Cieslik, W., et al.: Med Chem. 11, 771 (2015); Sosic, I., et al.: J. Med. Chem. 56, 521 (2013)
    Notice:Our products are intended for lab use only. For any other use, please contact us.

    Chemical properties

    Molecular weight:235.15
    Formula:C9H5N3O5
    Color/Form:Neat
    InChI:InChI=1S/C9H5N3O5/c13-9-7(12(16)17)4-6(11(14)15)5-2-1-3-10-8(5)9/h1-4,13H
    SMILES:O=[N+]([O-])c1cc([N+](=O)[O-])c2cccnc2c1O

    Technical inquiry about: 5,7-Dinitro-8-quinolinol

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