Diosgenin

CAS: 512-04-9

Ref. TR-D484700

Product Information

• Name: Diosgenin
• Synonyms: Spirost-5-en-3-ol, (3ß,25R)-, 25D-Spirost-5-en-3ß-ol (6CI,7CI), Spirost-5-en-3ß-ol, (25R)- (8CI), Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran], spirost-5-en-3-ol deriv., (25R)-Spirost-5-en-3ß-ol, (3ß,25R)-Spirost-5-en-3-ol, 25a-Spirost-5-en-3ß-ol, NSC 33396, Nitogenin, (20R,25R)-espirost-5-en-3β-ol, (20R,25R)-spirost-5-en-3-beta-ol, (20R,25R)-spirost-5-en-3β-ol, (20R,25R)-spirost-5-ene-3β-ol, (25R)-Spirost-5-en-3β-ol, (3beta,25R)-spirost-5-en-3-ol, (3beta,8xi,9xi,14xi,16xi,17xi,25R)-spirost-5-en-3-ol, (3β,25R)-Spirost-5-en-3-ol, (8xi,9xi,10xi,13xi,14xi,16xi,17xi,25R)-spirost-5-en-3-ol, 25<span class="text-smallcaps">D</span>-Spirost-5-en-3β-ol, 25D-Spirost-5-en-3β-ol, 25α-Spirost-5-en-3β-ol, Nsc 33396, Spiro[8H-naphth[2′,1′:4,5]indeno[2,1-b]furan-8,2′-[2H]pyran], spirost-5-en-3-ol deriv., Spirost-5-En-3-Ol, Spirost-5-en-3-ol, (3β,25R)-, Spirost-5-en-3β-ol, (25R)-, Wild Yam Extract

Description

Applications Aglicone of saponin dioscin. Diosgenin exists in some food supplements and herbal medicines and lowers plasma cholesterol by increasing fecal cholesterol excretion. It can be converted to Pregnenolone and Progesterone.
References Cayen, M., et al.: J. Lipid Res., 20, 162 (1979), Nervi, F., et al.: J. Clin. Invest., 74, 2226 (1984), Davis, H., et al.: J. Biol. Chem., 279, 33586 (2004), Brown, J., et al.: Biochem. J., 406, 273 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 414.62
• Formula: C₂₇H₄₂O₃
• Color/Form: White To Light Yellow
• InChI: InChI=1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
• InChI key: InChIKey=WQLVFSAGQJTQCK-XPMUQOCRSA-N
• SMILES: C[C@@H]1CC[C@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]3(C)[C@H]1[C@H]2C