2,2-Diphenylglycine

CAS: 3060-50-2

Ref. TR-D491620

Product Information

• Name: 2,2-Diphenylglycine
• Synonyms: Phenytoin Imp. C (EP),Phenytoin Sodium Imp. C (EP), Phenytoin USP Related Compound A, Phenytoin USP RC A, Amino(diphenyl)acetic Acid, Phenytoin Related Compound A, Phenytoin Impurity C, Phenytoin Sodium Impurity C, Phenytoin Impurity C, 2-Amino-2,2-diphenylacetic acid, Alpha-Aminodiphenylacetic Acid, Amino(Diphenyl)Acetic Acid, Benzeneacetic acid, α-amino-α-phenyl-, Glycine, 2,2-diphenyl-, NSC 33392, α,α-Diphenylglycine, α-Amino-α-phenylbenzeneacetic acid, α-Aminodiphenylacetic acid

Description

Impurity Phenytoin USP Related Compound A 2,2-Diphenylglycine
Stability Hygroscopic
Applications 2,2-Diphenylglycine (Phenytoin USP Related Compound A 2,2-Diphenylglycine) is a decomposition product of Phenytoin (D491650), which reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.
References Shah, V. et al.: J. Pharm. Sci., 75, 1113 (1986); Faucette, S., et al.: J. Pharmacol. Exp. Ther., 320, 72 (2007); Raymond, H. et al.: Teratol., 10, 237 (1974);

• Brand: TRC

Chemical properties

• Molecular weight: 227.26
• Formula: C₁₄H₁₃NO₂
• Color/Form: White To Off-White
• InChI: InChI=1S/C14H13NO2/c15-14(13(16)17,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,15H2,(H,16,17)
• InChI key: InChIKey=YBONNYNNFBAKLI-UHFFFAOYSA-N
• SMILES: NC(C(=O)O)(c1ccccc1)c1ccccc1