Diphenylpyraline Hydrochloride

CAS: 132-18-3

Ref. TR-D492113

Product Information

• Name: Diphenylpyraline Hydrochloride
• Synonyms: 1-Methyl-4-piperidyl Benzhydryl Ether Hydrochloride, 4-Diphenylmethoxy-1-methylpiperidine Hydrochloride, Anginosan, Belfene, Dayfen, Diafen, Diafen Hydrochloride, Diaphen, Diphenpyraline Hydrochloride, Diphenylpyraline Teoclate, Hispril, Hispril Hydrochloride, Histryl, Histyn, Kolton Jelly, Lergoban, Lergobine, Sumadil, 1-Methyl-4-piperidyl benzhydryl ether hydrochloride, 4-(Diphenyl methoxy)-1-piperidine HCl, 4-(Diphenylmethoxy)-1-Methylpiperidine Hydrochloride (1:1), 4-Benzhydryloxy-1-methylpiperidine~Diphenylpyraline hydrochloride, 4-Diphenylmethoxy-1-methylpiperidine hydrochloride, Diafen, Diafen (antihistamine), Diafen hydrochloride, Diphenpyraline hydrochloride, Diphenylpyraline hydrochloride, Diphenylpyraline teoclate, Hispril hydrochloride, Histryl Spansule Capsules, Piperidine, 4-(diphenylmethoxy)-1-methyl-, hydrochloride, Piperidine, 4-(diphenylmethoxy)-1-methyl-, hydrochloride (1:1)

Description

Stability Hygroscopic
Applications Diphenylpyraline Hydrochloride is a salt of Diphenylpyraline (D492110), an H1 receptor antagonist (an antihistamine) and is commonly prescribed to treat allergic and vasomotor rhinitis. There is also some research being conducted on diphenylpyraline derivatives to determine their antimycobacterial and antifungal activity.
References Kubo, N., et al.: Jpn. J. Pharmacol., 43, 277 (1987); Puhakka, H., et al.: J. Int. Med. Res., 5, 37 (1977); Sokoloff, O.: AMA Arch Derm Syphilol., 64, 754 (1951); Weis, R., et al.: Eur. J. Med. Chem., 43, 872 (2008);

• Brand: TRC

Chemical properties

• Molecular weight: 317.85
• Formula: C₁₉H₂₃NO·ClH
• Color/Form: White To Off-White
• InChI: /h2-11,18-19H,12-15H2,1H3, InChI=1S/C19H23NO.ClH/c1-20-14-12-18(13-15-20)21-19(16-8-4-2-5-9-16)17-10-6-3-7-11-17, 1H
• InChI key: InChIKey=LPRLDRXGWKXRMQ-UHFFFAOYSA-N
• SMILES: CN1CCC(OC(c2ccccc2)c2ccccc2)CC1.Cl