Product Information
Name:Donitriptan Hydrochloride
Synonyms:
- 4-[4-[2-[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-1-piperazinyl]benzonitrile Hydrochloride
- 1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl) piperazine Hydrochloride
- F 11356
Brand:TRC
Description:Applications A novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors in models relevant to migraine. An antimigraine agent.References Pauwels, P., et al.: Biochem. Pharmacol., 46, 535 (1993), Kleven, M., et al.: Eur. J. Pharmacol., 281, 219 (1995), Perez, M., et al.: J. Med. Chem., 38, 3602 (1995), Le Grand, B., et al.: J. Cardiovasc. Pharmacol., 32, 435 (1998),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:439.94
Formula:C23H25N5O2·HCl
Color/Form:Neat
InChI:InChI=1S/C23H25N5O2.ClH/c24-8-7-18-15-26-22-6-5-20(13-21(18)22)30-16-23(29)28-11-9-27(10-12-28)19-3-1-17(14-25)2-4-19;/h1-6,13,15,26H,7-12,16,24H2;1H
SMILES:Cl.N#Cc1ccc(N2CCN(C(=O)COc3ccc4[nH]cc(CCN)c4c3)CC2)cc1
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