Estimated delivery in United States, on Tuesday 21 Jan 2025
Product Information
Name:
Doravirine
Synonyms:
- Benzonitrile
- 3-chloro-5-[[1-[(4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]-
- 3-Chloro-5-[[1-[(4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile
- MK 1439
Description:
Applications Doravirine is a novel non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus.
References Feng, M., et al.: Antimicrob Agents Chemother, 60, 2241-7 (2016); Lai, M.T., et al.: Antimicrob Agents Chemother, 58, 1652-63 (2014); Anderson, M.S., et al.: Antivir Ther., 20, 397-405 (2015);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
425.75
Formula:
C17H11ClF3N5O3
Color/Form:
Neat
InChI:
InChI=1S/C17H11ClF3N5O3/c1-25-13(23-24-16(25)28)8-26-3-2-12(17(19,20)21)14(15(26)27)29-11-5-9(7-22)4-10(18)6-11/h2-6H,8H2,1H3,(H,24,28)
SMILES:
Cn1c(O)nnc1Cn1ccc(C(F)(F)F)c(Oc2cc(Cl)cc(C#N)c2)c1=O
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-D534255 Doravirine
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