Dorzolamide Hydrochloride

CAS: 130693-82-2

Ref. TR-D535100

Product Information

• Name: Dorzolamide Hydrochloride
• Synonyms: (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide Hydrochloride, L 671152, MK 507, Trusopt, (2S,4S)-2-Ethylamino-4-Methyl-5,5-Dioxo-5,7-Dithiabicyclo[4.3.0]Nona-8,10-Diene-8-Sulfonamide Hydrochloride, (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno-[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride, (4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride, (S,S)-(-)-5,6-Dihydro-4-ethylamino-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide monohydrochloride, 3-B)Thiopyran-2-Sulfonamide,5,6-Dihydro-4-(Ethylamino)-6-Methyl-4H-Thieno(, 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, hydrochloride (1:1), (4S,6S)-, 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S,6S)-, 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S-trans)-, Biosopt, Dorzalamide hydrochloride, Dorzolamide Hcl, DorzolomideHcl,Usp, Mk 507, Mk-0507, Monohydrochloride,(4S-Trans)-7-Dioxide

Description

Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.
References Lippa, E.A., et al.: Ophthalmology, 98, 308 (1991); Wang, R.-F., et al.: Arch. Ophthalmol., 109, 1297 (1991); Whikehart, D., et al.: J. Ocul. Pharmacol., 7, 195 (1991); Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998);

• Brand: TRC

Chemical properties

• Molecular weight: 360.90
• Formula: C₁₀H₁₆N₂O₄S₃·ClH
• Color/Form: Neat
• InChI: InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16, 1H/t6-,8-, /m0./s1, /h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)
• InChI key: InChIKey=OSRUSFPMRGDLAG-QMGYSKNISA-N
• SMILES: CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21.Cl