Dorzolamide N-Sulfonamide Dimer

CAS: 199734-72-0

Ref. TR-D535110

Product Information

• Name: Dorzolamide N-Sulfonamide Dimer
• Synonyms: (4R,6R)-rel-4-(Ethylamino)-N-[[(4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno[2,3-b]thiopyran-2-yl]sulfonyl]-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide
• Brand: TRC
• Description: Applications (4R,​6R)​-​rel-4-​(Ethylamino)​-​N-​[[(4S,​6S)​-​4-​(ethylamino)​-​5,​6-​dihydro-​6-​methyl-​7,​7-​dioxido-​4H-​thieno[2,​3-​b]​thiopyran-​2-​yl]​sulfonyl]​-​5,​6-​dihydro-​6-​methyl-4H-​thieno[2,​3-​b]​thiopyran-​2-​sulfonamide-7,7-dioxide is a byproduct from in-process test for synthesis of dorzolamide hydrochloride.References Thomas, S., et al.: At-Process, 2, 432 (1997).

Chemical properties

• Molecular weight: 631.85
• Formula: C₂₀H₂₉N₃O₈S₆
• Color/Form: Off White
• InChI: InChI=1S/C20H29N3O8S6/c1-5-21-15-7-11(3)34(24,25)19-13(15)9-17(32-19)36(28,29)23-37(30,31)18-10-14-16(22-6-2)8-12(4)35(26,27)20(14)33-18/h9-12,15-16,21-23H,5-8H2,1-4H3/t11-,12-,15-,16-/m0/s1
• InChI key: InChIKey=OTVNOYKKKXGTOL-APYUEPQZSA-N
• SMILES: CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(S(=O)(=O)NS(=O)(=O)c3cc4c(s3)S(=O)(=O)[C@@H](C)C[C@@H]4NCC)cc21