Doxazosin Mesylate

CAS: 77883-43-3

Ref. TR-D537500

Product Information

• Name: Doxazosin Mesylate
• Synonyms: Doxazosin Mesilate, Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2,3-dihydro-1,4-benzodioxin-2-yl)-, methanesulfonate (1:1), Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, monomethanesulfonate (9CI), 1,4-Benzodioxin, piperazine deriv., Alfadil, Cardenalin, Cardran, Cardular, Cardura, Cardura (pharmaceutical), Carduran, Diblocin, Doxazosin monomethanesulfonate, Normothen, Supressin, UK 33274-27
• Brand: TRC

Description

Stability Light Sensitive
Applications Doxazosin is a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.
References Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982), de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982),

Chemical properties

• Molecular weight: 547.58
• Formula: C₂₃H₂₅N₅O₅·CH₄O₃S
• Color/Form: Neat
• InChI: InChI=1S/C23H25N5O5.CH4O3S/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20;1-5(2,3)4/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26);1H3,(H,2,3,4)
• InChI key: InChIKey=VJECBOKJABCYMF-UHFFFAOYSA-N
• SMILES: COc1cc2nc(N3CCN(C(=O)C4COc5ccccc5O4)CC3)nc(N)c2cc1OC.CS(=O)(=O)O