Product Information
Name:dTAG-7
Controlled Product
Synonyms:
- (2S)-2-Piperidinecarboxylic Acid 1-[(2S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-
- (1R)-3-(3,4-dimethoxyphenyl)-1-[2-[[19-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-2,18-dioxo-7,10,13-trioxa-3,17-diazanonadec-1-yl]oxy]phenyl]propyl Ester
Brand:TRC
Description:Applications dTAG-7 is a degradation tag which was tested for its efficiency at depleting FKBP12F36V -MELK(sg3R) and was found to have significantly degraded FKBP12F36V -MELK(sg3R) within 4 hours.Used in the study of cancer research.References Hai-Tsang Huang., eLife, 1-29, (2017)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1210.32
Formula:C63H79N5O19
Color/Form:Neat
InChI:InChI=1S/C63H79N5O19/c1-7-42(41-36-52(79-4)58(81-6)53(37-41)80-5)60(73)67-28-11-10-17-46(67)63(76)87-48(23-20-40-21-24-49(77-2)51(35-40)78-3)43-15-8-9-18-47(43)85-38-55(70)64-26-13-29-82-31-33-84-34-32-83-30-14-27-65-56(71)39-86-50-19-12-16-44-57(50)62(75)68(61(44)74)45-22-25-54(69)66-59(45)72/h8-9,12,15-16,18-19,21,24,35-37,42,45-46,48H,7,10-11,13-14,17,20,22-23,25-34,38-39H2,1-6H3,(H,64,70)(H,65,71)(H,66,69,72)/t42-,45?,46-,48+/m0/s1
InChI key:InChIKey=CUPXCNJJCAENKR-HQKXCPIYSA-N
SMILES:CC[C@H](CN1CCCC[C@H]1CO[C@H](CCc1ccc(OC)c(OC)c1)c1ccccc1OCC(=O)NCCCOCCOCCOCCCNC(=O)COc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O)c1cc(OC)c(OC)c(OC)c1
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