Edaravone D5

CAS: 1228765-67-0

Ref. TR-E122872

Product Information

• Name: Edaravone D5
• Synonyms: 5-methyl-2-(2,3,4,5,6-pentadeuteriophenyl)-4H-pyrazol-3-one

Description

Applications Edaravone D5 is the labelled compound of Edaravone(E335000). synthesized and used for relative quant. anal. of oligosaccharides by mass spectrometry (MS). Edaravone inhibits the disease activity in rheumatoid arthritis. Edaravone can significantly enhance IR flap viability and protect flap vessels, which is related to scavenging oxygen free radicals, reducing the consumption of SOD, reducing the extent of lipid peroxidation and inflammation, and protecting functional structure of vessels in the early stages of reperfusion. It also shows protective effects against STZ-induced cognitive impairment, oxidative stress, cholinergic dysfunction and altered protein expressions. Its acts like a free radical scavenger, decreased apoptotic cell death, oxidative damage to DNA and lipids, and angiogene
References Zhang, Ping, et al.: Anal. Biochem., 418, 1(2011)

• Brand: TRC

Chemical properties

• Molecular weight: 179.23
• Formula: C₁₀D₅H₅N₂O
• Color/Form: Off-White
• InChI: InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3/i2D,3D,4D,5D,6D
• InChI key: InChIKey=QELUYTUMUWHWMC-VIQYUKPQSA-N
• SMILES: [2H]c1c([2H])c([2H])c(N2N=C(C)CC2=O)c([2H])c1[2H]