Emtricitabine Glycosamine

Ref. TR-E253540

Product Information

• Name: Emtricitabine Glycosamine
• Synonyms: 4-[[3,4-dihydroxy-6-(hydroxymethyl)-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]amino]-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

Description

Applications Emtricitabine Glycosamine is an impurity of Emtricitabine(E525000) which is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 571.528
• Formula: C₂₀H₃₀FN₃O₁₃S
• Color/Form: Neat
• InChI: InChI=1S/C20H30FN3O13S/c21-6-1-24(9-5-38-10(4-27)36-9)20(33)23-17(6)22-18-14(31)13(30)16(8(3-26)34-18)37-19-15(32)12(29)11(28)7(2-25)35-19/h1,7-16,18-19,25-32H,2-5H2,(H,22,23,33)
• InChI key: InChIKey=PVWPATKYBSBQIS-UHFFFAOYSA-N
• SMILES: O=c1nc(NC2OC(CO)C(OC3OC(CO)C(O)C(O)C3O)C(O)C2O)c(F)cn1C1CSC(CO)O1